منابع مشابه
Calcium sparks.
The calcium ion (Ca(2+)) is the simplest and most versatile intracellular messenger known. The discovery of Ca(2+) sparks and a related family of elementary Ca(2+) signaling events has revealed fundamental principles of the Ca(2+) signaling system. A newly appreciated "digital" subsystem consisting of brief, high Ca(2+) concentration over short distances (nanometers to microns) comingles with a...
متن کاملTemplates in Creative Sparks
We question whether creativity requires functions exclusive to the human mind or it can rather be obtained by the mere performance of well-defined prescribed operations. The natural thinking process involves a complexity of sensory inputs, psychological factors, cognitive background, social rules and constraints which interfere (constructively and at times, destructively) with the results and e...
متن کاملPerspectives on Ca2+ Sparks
The purpose of the Perspectives in General Physiology is to provide a forum where scientific uncertainties or controversies can be discussed in an authoritative, yet open manner. The Perspectives are solicited by the editors—often based on recommendations by the advisory editors or members of the editorial board, who may be asked to coordinate the process. To frame the issue, two or more expert...
متن کاملD-bar Sparks
A ∂-analogue of differential characters for complex manifolds is introduced and studied using a new theory of homological spark complexes. Many essentially different spark complexes are shown to have isomorphic groups of spark classes. This has many consequences: It leads to an analytic representation of O-gerbes with connection, it yields a soft resolution of the sheaf O by currents on the man...
متن کاملAged muscle lacks sparks
609 M uscle activity is driven by spikes of calcium release. Weisleder et al. (page 639) fi nd that aged muscles, when compared with young muscles, have reduced Ca 2+ release following stimulation. The dampened response may be caused by a failure to maintain robust membranous compartments that can respond to an input with a single output. Previous work from the group showed that Ca 2+ sparks ca...
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ژورنال
عنوان ژورنال: Journal of Synchrotron Radiation
سال: 2004
ISSN: 0909-0495
DOI: 10.1107/s0909049504014402